Channel 108459-kca

General data

• ICG id: 86
• ModelDB id: 108459
• Reference: Letzkus JJ, Kampa BM, Stuart GJ (2006): Learning rules for spike timing-dependent plasticity depend on dendritic synapse location.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: not specified

Metadata generic

• Age: 3-6 weeks old
• Authors: Z Mainen
• Comments: Calcium-dependent potassium channel, based on pennefather (1990) for sympathetic ganglion cells, taken from reuveni et al. (1993) for neocortical cells. Written by z mainen 1995. Taken from schaefer et al. (2003), model no. 83344. Experiments and modeling -- animal model info is from experimental methods, but the modeling morphology is also from a l5 pyramidal neuron (stuart & spruston, 1998).
• Runtime: 67.745
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C. Simulations done at 35 deg C. NOTE: see original ancestor mod file (mod no. 2488) for note about temperature.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp