Channel 128559-iKCa

General data

• ICG id: 800
• ModelDB id: 128559
• Reference: Aguiar P, Sousa M, Lima D (2010): NMDA channels together with L-type calcium currents and calcium-activated nonspecific cationic currents are sufficient to generate windup in WDR neurons.

Metadata classes

• Brain Area: dorsal horn of spinal cord
• Neuron Type: wide dynamic range (WDR) neuron
• Runtime Q: Q2
• Subtype: AHP

Metadata generic

• Authors: A Destexhe, Y Poirazi
• Comments: Slow ca-dependent potassium current, responsible for slow ahp, from destexhe et al. (1994). The saturation point for the concentration of intracellular calcium was reduced. Taken from poirazi et al. (2003), model no. 20212, with no apparent changes to kinetics. Modeling study, with no mention of animal model. Channel kinetics come from various previous models of other neurons in other brain regions. This channel was previously used in a model of hippocampus.
• Runtime: 71.752
• Temperature: Model has temperature dependence, with q10 assumed to be 3. Original kinetics were formulated at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp