Channel 122329-sk_gp

General data

• ICG id: 474
• ModelDB id: 122329
• Reference: Deister CA, Chan CS, Surmeier DJ, Wilson CJ (2009): Calcium-activated SK channels influence voltage-gated ion channels to determine the precision of firing in globus pallidus neurons.

Metadata classes

• Animal Model: mouse, rat
• Brain Area: basal ganglia, globus pallidus (GP)
• Neuron Type: globus pallidus (GP) neuron
• Runtime Q: Q2
• Subtype: SK

Metadata generic

• Age: P15-25 (rat), P17-22 (mouse)
• Authors: J Held, C Deister
• Comments: Sk current. Taken from mercer et al. (2007), model no. 105385, with the following modifications: deactivation rate constant reduced by a factor of ~10 (from .5e-2 to 0.06, line 25). Animal model is from experiments in paper, channel kinetics come from previous study of gp (mercer et al. 2007).
• Runtime: 69.439
• Temperature: Model has temperature dependence, original at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp