Channel 150024-SK

General data

• ICG id: 3184
• ModelDB id: 150024
• Reference: Ovsepian SV, Steuber V, Le Berre M, O'Hara L, O'Leary VB, Dolly JO (2013): A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets.

Metadata classes

• Animal Model: rat
• Brain Area: cerebellum, distal cerebellar nucleus (DCN)
• Neuron Region: soma, dendrites
• Runtime Q: Q3
• Subtype: SK

Metadata generic

• Age: P75-90
• Authors: J Luthman, V Steuber
• Comments: Small conductance calcium dependent potassium current (sk) of deep cerebellar nucleus (dcn) neuron. This channel’s conductance is affected by the calcium concentration which has been accumulated through the cahva channel and kept track of by caconc.mod. Calcium entry through the calva channel is kept track of by calconc.mod and doesn’t affect the sk channel. Translated from genesis by j luthman and v steuber. Channel kinetics came from previous models in steuber et al. (2011) (genesis) and luthman et al. (2011) (neuron). This mod file was taken from luthman et al. (2011), model no. 144523, with no changes (identical mod file). Animal model comes from experiments in this paper. Morphology used is from rat (p14-17) in steuber et al. (2004), and channel kinetics come from previous studies (luthman et al. 2011, steuber et al. 2011) also on dcn neurons in rat (p13-19)
• Runtime: 72.362
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp