Channel 98005-bk_ch

General data

• ICG id: 2641
• ModelDB id: 98005
• Reference: Maurice N, Mercer J, Chan CS, Hernandez-Lopez S, Held J, Tkatch T, Surmeier DJ (2004): D2 dopamine receptor-mediated modulation of voltage-dependent Na+ channels reduces autonomous activity in striatal cholinergic interneurons.

Metadata classes

• Animal Model: Sprague-Dawley, mouse, rat, C57BL/6
• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Region: soma, dendrites
• Neuron Type: interneuron, cholinergic
• Runtime Q: Q4 (slow)
• Subtype: BK

Metadata generic

• Age: 3-5 weeks
• Authors: NW Gouwens
• Comments: Bk-type purkinje calcium-activated potassium current. Taken from khaliq et al. (2003), model no. 48332, with no modification to kinetics. Animal model is from experiments in paper. Bk channel kinetics come from previous model of purkinje cells (khaliq et al. 2003).
• Runtime: 78.361
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp