Channel 115356-KAHP

General data

• ICG id: 259
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: AHP

Metadata generic

• Age: 17-21 days
• Authors: M Horstmann.
• Comments: K-ahp current from stacey, durand 2000, ek from martina. Also from warman et al (1994). No model db ancestors. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics from stacey & durand (2000) and warman et al. (1994). The animal model info here is from the experiments in this paper.
• Runtime: 78.347
• Temperature: Model has no temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp