Channel 20212-cagk

General data

• ICG id: 1624
• ModelDB id: 20212
• Reference: Polsky A, Mel BW, Schiller J (2004): Computational subunits in thin dendrites of pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, apical trunk
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: AHP

Metadata generic

• Authors: M Hines, B Mel, Y Poirazi
• Comments: Calcium activated mahp k channel, from moczydlowski and latorre (1983), model no. 3509, with several modifications. It is unclear if kinetics have been changed. This is a modeling study, and the animal model is considered to be rat. The authors compare the model to experimental results mostly in rats (e.g. Magee 1998, spruston et al. 1995) and the morphology used is also from rat (2 months old, cannon et al. 1998, n123). Channel kinetics come from various sources.
• Runtime: 75.8
• Temperature: Model has temperature dependence. Simulations were done at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp