Channel 144526-Kca

General data

• ICG id: 1472
• ModelDB id: 144526
• Reference: Hallermann S, de Kock CP, Stuart GJ, Kole MH (2012): State and location dependence of action potential metabolic cost in cortical pyramidal neurons.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Age: 3-5 weeks old
• Authors: Z Mainen, S Hallermann, M Kole
• Comments: Calcium-dependent potassium channel based on pennefather (1990) for sympathetic ganglion cells taken from reuveni et al. (1993) for neocortical cells, written by z mainen 1995. Modified by kole according to schaefer et al. (2003) to allow bac firing, caix increased to 4. Adapted from mainen & sejnowski (1996), model no. 2488. Electrophysiological recordings with modeling from previously created models. The animal model info is from the experimental data. The neuronal morphology for the model came from experimental reports from in vivo and in vitro l5 pyramidal neurons.
• Runtime: 69.989
• Temperature: Simulations done at 33 deg C and 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp