Channel 112359-IhDA

General data

• ICG id: 94
• ModelDB id: 112359
• Reference: Migliore M, Cannia C, Canavier CC (2008): A modeling study suggesting a possible pharmacological target to mitigate the effects of ethanol on reward-related dopaminergic signaling.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, ventral tegmental area (VTA), substantia nigra pars compacta (SNc)
• Neuron Region: soma, dendrites
• Neuron Type: dopaminergic
• Runtime Q: Q3
• Subtype: h

Metadata generic

• Age: not specified
• Authors: M Migliore
• Comments: I-h channel from magee 1998 for distal dendrites. No apparent modeldb ancestors. Modeling study based on a previous model (canavier & landry 2006; komendantov et al. 2004). Animal model comes from these previous studies. In this paper, model is compared to data from mouse midbrain dopamine neurons (okamoto et al. 2006)
• Runtime: 14.195
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp