Channel 126776-h

General data

• ICG id: 719
• ModelDB id: 126776
• Reference: Ascoli GA, Gasparini S, Medinilla V, Migliore M (2010): Local control of postinhibitory rebound spiking in CA1 pyramidal neuron dendrites.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: h

Metadata generic

• Age: 8-12 weeks old
• Authors: M Migliore
• Comments: I-h channel from magee 1998 for distal dendrites, modified to take into account sonia's exp. Apr. 2008, by m. Migliore. From m migliore et al. (2005), model no. 55035, with changes to parameters vhalf, a0t, zetat and gmt (lines 17-20). This paper contains electrophysiological experiments on rats as well as modeling based on migliore et al. (2005), using the same kinetics and morphology. The animal model info is from the experimental results in this paper, the morphology is the same, except that the rats are 6-12 weeks old instead of 12.
• Runtime: 14.695
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp