Channel 155601-hyperde3

General data

• ICG id: 3335
• ModelDB id: 155601
• Reference: Proddutur A, Yu J, Elgammal FS, Santhakumar V (2013): Seizure-induced alterations in fast-spiking basket cell GABA currents modulate frequency and coherence of gamma oscillation in network simulations.

Metadata classes

• Animal Model: rat
• Brain Area: dentate gyrus (DG)
• Neuron Region: soma, dendrites
• Neuron Type: basket cell, fast-spiking (FS) cell
• Runtime Q: Q2
• Subtype: h

Metadata generic

• Age: P30-35
• Authors: I Aradi
• Comments: Distal dendritic ih channel kinetics for both ht and control, from chen et al. (2001). Taken from santhakumar et al. (2005), model no. 51781 (and 124513), with no changes (identical mod file). Animal model is from experiments in the paper, channel kinetics were previously used in dg network model (santhakumar et al. 2005).
• Runtime: 13.206
• Temperature: Model has temperature dependence, with q10 set to 3.0 and original kinetics at 6.3 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp