Channel 149174-hyperde3

General data

• ICG id: 3274
• ModelDB id: 149174
• Reference: Thomas EA, Petrou S (2013): Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, dentate gyrus (DG)
• Neuron Region: unspecified
• Neuron Type: granule cell, basket cell, hilar mossy cell, hilar perforant-path associated (HIPP) cell
• Runtime Q: Q2
• Subtype: h

Metadata generic

• Age: P18-P22
• Authors: I Aradi
• Comments: Distal dendritic ih channel kinetics both both ht and control animals. From chen et al. (2001), by i aradi. Taken from santhakumar et al. (2005), model no. 51781, with no changes (identical mod file). Modeling study. Animal model is from model and ancestor for channels (santakumar et al. 2005), originally from aradi and holmes (1999), among others.
• Runtime: 13.479
• Temperature: Model has temperature dependence, with original kinetics at 6.3 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp