Channel 102288-Ih

General data

• ICG id: 21
• ModelDB id: 102288
• Reference: Lawrence JJ, Saraga F, Churchill JF, Statland JM, Travis KE, Skinner FK, McBain CJ (2006): Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: oriens lacunosum-moleculare (O-LM), interneuron
• Runtime Q: Q1 (fast)
• Subtype: h

Metadata generic

• Age: 3-6 months old
• Authors: F Saraga
• Comments: Ih current (hyperpolarization-activated nonspecific na and k channel) for ca1 pyramidal cells, based on the following: maccaferri and mcbain (1996), maccaferri et al. (1993), pape (1996) and magee (1998). Taken from saraga et al. (2003), model no. 28316, with some small changes but no apparent modification to kinetics. Experimental results for im potassium current along with modeling. The animal model info here is from experimental results in the paper.
• Runtime: 12.958
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp