Channel 32992-h

General data

• ICG id: 1777
• ModelDB id: 32992
• Reference: Migliore M, Messineo L, Ferrante M (2004): Dendritic Ih selectively blocks temporal summation of unsynchronized distal inputs in CA1 pyramidal neurons.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: h

Metadata generic

• Age: 5-8 weeks old
• Authors: M Migliore
• Comments: I-h channel from magee (1998) for distal dendrites. Likely from poolos et al. (2002), model no. 9769, (although this is not clear from the paper) with the following modifications: vhalf set to 81 (line 14), additional parameter kl (lines 15, 74), removal of function alpl. Model is the same as ancestor, so the animal model info here is that of the ancestor model.
• Runtime: 13.97
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp