Channel 144541-h

General data

• ICG id: 1481
• ModelDB id: 144541
• Reference: Migliore M, Migliore R (2012): Know your current I(h): interaction with a shunting current explains the puzzling effects of its pharmacological or pathological modulations.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: h

Metadata generic

• Age: 8-12 weeks old
• Authors: M Migliore.
• Comments: I-h channel from magee 1998 for distal dendrites, default values are for dendrites and low na plus leakage, implemented by m migliore mar 2010. From ascoli et al. (2010), model no. 126776, but modified in this paper to fit new data, such as in narayanan & johnston (2007). Modeling study, with identical kinetics and morphology to ancestor model.
• Runtime: 14.529
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp