Channel 144520-if

General data

• ICG id: 1443
• ModelDB id: 144520
• Reference: DiFrancesco D, Noble D (1985): A model of cardiac electrical activity incorporating ionic pumps and concentration changes.

Metadata classes

• Animal Model: mammal
• Brain Area: heart
• Neuron Region: unspecified
• Neuron Type: sinoatrial cell (Purkinje fibers)
• Runtime Q: Q4 (slow)
• Subtype: h

Metadata generic

• Authors: F Gannier
• Comments: Sodium/calcium cardiac hyperpolarizing if current (hcn4), modified from difrancesco & noble (1985), for neuron by fe gannier. No model db ancestors. Kinetics and parameters based on various sources, see paper for details. Modeling study that uses various experimental and previous modeling results. Channel model is listed as nonspecific ion type, due to sodium and calcium components.
• Runtime: 14.78
• Temperature: Model has no temperature dependence. Default is 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp