Channel 229585-Cav3_2

General data

• ICG id: 4174
• ModelDB id: 229585
• Reference: Masoli S, Solinas S, D'Angelo E (2015): Action potential processing in a detailed Purkinje cell model reveals a critical role for axonal compartmentalization.

Metadata classes

• Animal Model: guinea pig
• Brain Area: cerebellum
• Neuron Region: unspecified
• Neuron Type: Purkinje cell
• Subtype: not specified

Metadata generic

• Age: 2–3 months old
• Authors: Masoli S, Solinas S, D'Angelo E
• Comments: TITLE Low threshold calcium current : : Ca++ current responsible for low threshold spikes (LTS) : RETICULAR THALAMUS : Differential equations : : Model of Huguenard & McCormick, J Neurophysiol 68: 1373-1383, 1992. : : Written by Alain Destexhe, Salk Institute, Sept 18, 1992 : : - Biophysical properties of the T current were from recordings of : - human recombinant Cav3.2 T-channel in HEK-293 cells : - see Vitko et al., J. Neurosci 25(19) :4844-4855, 2005 : - Q10 and shift parameters are fixed : : : Suffix from CaT3_2 to Cav3_2
• Temperature: no temperature dependence

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp