Channel 155568-LcaMig

General data

• ICG id: 3348
• ModelDB id: 155568
• Reference: Tejada J, Garcia-Cairasco N, Roque AC (2014): Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, dentate gyrus (DG)
• Neuron Region: soma, dendrites
• Neuron Type: granule cell, basket cell, hilar mossy cell, hilar perforant-path associated (HIPP) cell
• Runtime Q: Q2
• Subtype: L-type

Metadata generic

• Authors: M Migliore
• Comments: L-type calcium channel. One paper references aradi and holmes (1999, 2002) for kinetics and parameters, while the other references santhakumar et al. (2005). We cite santhakumar et al. (2005), model no. 51781, because all mod files are identical. Modeling study, with identical kinetics to ancestor, santhakumar et al. (2005). Animal model is as specified in paper and ancestors. Age is not clear.
• Runtime: 7.709
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp