Channel 151458-caL13

General data

• ICG id: 3037
• ModelDB id: 151458
• Reference: Nakano T, Yoshimoto J, Doya K (2013): A model-based prediction of the calcium responses in the striatal synaptic spines depending on the timing of cortical and dopaminergic inputs and post-synaptic spikes.

Metadata classes

• Animal Model: mouse
• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q2
• Subtype: L-type

Metadata generic

• Age: P21-25
• Authors: J Moyer
• Comments: Lva l-type (1.3) calcium channel for nucleus accumbens neuron w/ inact, using ghk formulation, by j moyer 2004. Taken from wolf et al. (2005), model no. 112834, with the following modifications: variable mu added (lines 18, 58, 69) and mshift set to value that depends on mu (line 69). Modeling study, the animal model here is from the morphology explained in this paper. Channel kinetics based on previous model of msp in nucleus accumbens of rats.
• Runtime: 7.742
• Temperature: Model has temperature dependence. Simulations done at 35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp