Channel 150240-IT

General data

• ICG id: 2967
• ModelDB id: 150240
• Reference: Behuret S, Deleuze C, Gomez L, Fregnac Y, Bal T (2013): Cortically-controlled population stochastic facilitation as a plausible substrate for guiding sensory transfer across the thalamic gateway.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: cortex, retina, thalamocortical circuit, layer 4
• Neuron Region: unspecified
• Neuron Type: pyramidal cell, thalamocortical relay cell (TC, TCR)
• Runtime Q: Q3
• Subtype: T-type

Metadata generic

• Age: 4-6 weeks, 14-25 days
• Authors: A Destexhe
• Comments: Low threshold ca current, in thalamocortical cells. Based on data from huguenard & mccormick (1992), and huguenard & prince (1992). Written by a destexhe, 1993, modified in 1995. Ancestor channel from destexhe et al. (1998, 2001), model no. 3817, with the following change: solver method changed from cnexp to euler (line 66). Paper also cites destexhe et al. 1996 (model no. 3343). Paper features in vitro experiments on rat thalamus, which are used along with the model. Parameter values for active kinetics may have been changed to fit voltage clamp data in this paper.
• Runtime: 7.884
• Temperature: q10 set to 3, default temperature of 36 deg C, modified by this q10.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp