Channel 146565-ca

General data

• ICG id: 2860
• ModelDB id: 146565
• Reference: Lavzin M, Rapoport S, Polsky A, Garion L, Schiller J (2012): Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo.

Metadata classes

• Animal Model: mouse, rat
• Brain Area: cortex, layer 4, barrel cortex
• Neuron Type: stellate cell, spiny cell
• Runtime Q: Q1 (fast)
• Subtype: HVA

Metadata generic

• Age: P15-20 (mouse, in vitro), P27-35 (rat, in vivo)
• Authors: Z Mainen
• Comments: Hva ca current, based on reuveni, friedman, amitai and gutnick (1993), by z mainen 1994. Aug 2002: modification of regional channel to allow variable time step and to correct an initialization error. Done by m hines and r scorcioni. Designed to be run only at 37 deg c. No mention of ancestors in paper, but this is originally from mainen & sejnowski (1996), model no. 2488, with different rate kinetics (lines 156-157). Animal model here is from experiments in paper. Model uses unspecified morphology and kinetics for a spiny stellate cell. This channel was used previously in a model of l5 pyramidal cell (mainen et al. 1996).
• Runtime: 7.267
• Temperature: Model has temperature dependence, but is not meant to be used at any temperature other than 37 deg C. Original kinetics were at 23 deg C, and q10 is 2.3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp