Channel 9889-IT2_huguenard

General data

• ICG id: 2678
• ModelDB id: 9889
• Reference: Lytton WW, Contreras D, Destexhe A, Steriade M (1997): Dynamic interactions determine partial thalamic quiescence in a computer network model of spike-and-wave seizures.

Metadata classes

• Animal Model: cat
• Brain Area: thalamus
• Neuron Type: thalamocortical relay cell (TC, TCR), thalamic reticular (RE) cell
• Runtime Q: Q4 (slow)
• Subtype: T-type

Metadata generic

• Age: adult
• Authors: A Destexhe
• Comments: Low-threshold ca current, responsible for low threshold spikes (lts), for reticular thalamus. Model of huguenard & mccormick (1992), from data by huguenard & prince (1992). Written by a destexhe sept 1992. The paper references destexhe et al. 1993 for all v-gated channels and calcium pump. Model taken from destexhe et al. 1994, model no. 3670, with modified parameters. Modeling study, with animal model from previous experimental results used in the paper (steriade and contreras 1995).
• Runtime: 9.493
• Temperature: Model has temperature dependence, with original kinetics at 24 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp