Channel 98005-cap_ch

General data

• ICG id: 2644
• ModelDB id: 98005
• Reference: Maurice N, Mercer J, Chan CS, Hernandez-Lopez S, Held J, Tkatch T, Surmeier DJ (2004): D2 dopamine receptor-mediated modulation of voltage-dependent Na+ channels reduces autonomous activity in striatal cholinergic interneurons.

Metadata classes

• Animal Model: Sprague-Dawley, mouse, rat, C57BL/6
• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Region: soma, dendrites
• Neuron Type: interneuron, cholinergic
• Runtime Q: Q3
• Subtype: P-type

Metadata generic

• Age: 3-5 weeks
• Authors: NW Gouwens
• Comments: Hh p-type calcium current. I believe that this is the cav2.1 channel. From khaliq et al. (2003), model no. 48332, with no modification to kinetics. Animal model is from experiments in paper. P-type calcium channel kinetics come from previous model of cerebellar purkinje cell (khaliq et al. 2003).
• Runtime: 7.797
• Temperature: Model has temperature dependence, but note that it is stored using variable T, not the normal celsius.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp