Channel 115356-CAR

General data

• ICG id: 253
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: R-type

Metadata generic

• Age: 17-21 days
• Authors: M Horstmann.
• Comments: Ca-r channel, gates dimitri, taus from randall and tsien (1997), own ghk, t-dependence from mcallister-williams and kelly (1995). Parameters from sochivko et al. (2003). No model db ancestors. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics from various sources. The animal model info here is from the experiments in this paper.
• Runtime: 8.619
• Temperature: Model has temperature dependence, with q10 from McAllister-Williams & Kelly (1995).

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp