Channel 87284-can2

General data

• ICG id: 2466
• ModelDB id: 87284
• Reference: Morse TM, Carnevale NT, Mutalik PG, Migliore M, Shepherd GM (2010): Abnormal Excitability of Oblique Dendrites Implicated in Early Alzheimer's: A Computational Study.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: N-type

Metadata generic

• Age: 7-14 weeks old.
• Authors: M Migliore.
• Comments: N-type calcium channel. From hemond et al. (2008), model no. 101629, with no changes (identical mod file). Animal model taken from chen (2005) which is used to constrain model. Channel kinetics from previous study on hippocampal pyramidal neuron (hemond et al. 2008)
• Runtime: 8.585
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp