Channel 82849-hva

General data

• ICG id: 2393
• ModelDB id: 82849
• Reference: Durstewitz D, Seamans JK, Sejnowski TJ (2000): Dopamine-mediated stabilization of delay-period activity in a network model of prefrontal cortex.

Metadata classes

• Animal Model: rat
• Brain Area: layer 5, prefrontal cortex, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: HVA

Metadata generic

• Age: 14-28 days
• Authors: D Durstewitz
• Comments: High voltage activated ca2+ current. Consists of both l- and n-type channels, model taken from brown et al. (1993), also cites hell et al. (1993), schiller et al. (1995), seamans et al. (1997), and westenbroek et al. (1989). No modeldb ancestors. Animal model is from experiments in paper. Channel model was adapted from previous model of rat neocortex (brown et al. 1993). NOTE: this file is not temperature dependent, and so the calculation of the reversal potential may be off depending on the simulation temperature.
• Runtime: 7.568
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp