Channel 53569-CaT

General data

• ICG id: 2108
• ModelDB id: 53569
• Reference: Prescott SA, De Koninck Y (2005): Integration time in a subset of spinal lamina I neurons is lengthened by sodium and calcium currents acting synergistically to prolong subthreshold depolarization.

Metadata classes

• Animal Model: rat
• Brain Area: spinal cord
• Neuron Region: soma, dendrites
• Neuron Type: fusiform neuron
• Runtime Q: Q3
• Subtype: T-type

Metadata generic

• Age: adult (>40 days)
• Authors: A Destexhe, A Houweling, S Prescott
• Comments: Low threshold calcium current responsible for lts in reticular thalamus, from model of huguenard & mccormick (1992), written by a destexhe sept 1992, modified by s prescott 2005. Mod file taken from houweling and sejnowski (1997), model no. 3808, with modified gcabar and the addition of shift parameters vdm and vsh. Animal model is from experiments in paper.
• Runtime: 7.893
• Temperature: Model has temperature dependence, with original kinetics at 24 deg C, and q10 values set to 5.0 and 3.0 for m and h gating variables, respectively. Simulations were done at 23 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp