Channel 20212-it

General data

• ICG id: 1650
• ModelDB id: 20212
• Reference: Polsky A, Mel BW, Schiller J (2004): Computational subunits in thin dendrites of pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: low threshold

Metadata generic

• Authors: A Destexhe
• Comments: Low threshold calcium current responsible for low threshold spikes (lts) in reticular thalamus. Model from huguenard & mccormick (1992) and huguenard & prince (1992), written by a destexhe sept 1992. Not used in main model implementation here [found in not-currently-used folder]. From destexhe et al. (1996), model no. 3343. This is a modeling study, and the animal model is considered to be rat. The authors compare the model to experimental results mostly in rats (e.g. Magee 1998, spruston et al. 1995) and the morphology used is also from rat (2 months old, cannon et al. 1998, n123). Channel kinetics come from various sources.
• Runtime: 8.187
• Temperature: Model has temperature dependence, with q10 set to 5.0 for m variable and 3.0 for h variable, and original kinetics at 24 deg C for both. Simulations were done at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp