Channel 20212-calH

General data

• ICG id: 1627
• ModelDB id: 20212
• Reference: Polsky A, Mel BW, Schiller J (2004): Computational subunits in thin dendrites of pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: dendrites, apical trunk
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: L-type

Metadata generic

• Authors: Y Poirazi
• Comments: Ca l-type channel with high threshold for activation, inserted in distal dendrites to account for distally restricted initiation of ca2+ spikes, uses channel conductance. Written by y poirazi jan 2000. Adapted from magee and johnston (1995). No modeldb ancestors. This is a modeling study, and the animal model is considered to be rat. The authors compare the model to experimental results mostly in rats (e.g. Magee 1998, spruston et al. 1995) and the morphology used is also from rat (2 months old, cannon et al. 1998, n123). Channel kinetics come from various sources.
• Runtime: 7.429
• Temperature: Model has temperature dependence. Simulations were done at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp