Channel 19920-ca_a1i

General data

• ICG id: 1586
• ModelDB id: 19920
• Reference: McRory JE, Santi CM, Hamming KS, Mezeyova J, Sutton KG, Baillie DL, Stea A, Snutch TP (2001): Molecular and functional characterization of a family of rat brain T-type calcium channels.

Metadata classes

• Animal Model: rat
• Brain Area: generic
• Runtime Q: Q3
• Subtype: T-type

Metadata generic

• Age: adult
• Authors: M Migliore
• Comments: Cat channel alpha-1i from mcrory et al. (2001), model from huguenard & mccormick (1992), implemented by m. Migliore jan 2003. No apparent modeldb ancestors. Animal model is from the genetic experiments in paper. Different areas of the brain were used, so the brain area and neuron type are considered generic. The channel kinetics were fit to a model previously used in thalamocortical relay neurons in young rats (huguenard & mccormick 1992).
• Runtime: 8.06
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp