Channel 112834-car

General data

• ICG id: 146
• ModelDB id: 112834
• Reference: Wolf JA, Moyer JT, Lazarewicz MT, Contreras D, Benoit-Marand M, O'Donnell P, Finkel LH (2005): NMDA/AMPA ratio impacts state transitions and entrainment to oscillations in a computational model of the nucleus accumbens medium spiny projection neuron.

Metadata classes

• Animal Model: rat
• Brain Area: basal ganglia, nucleus accumbens (NAcc)
• Neuron Region: soma, dendrites
• Neuron Type: medium spiny projection (MSP) neuron
• Runtime Q: Q4 (slow)
• Subtype: R-type

Metadata generic

• Age: 48-59 days
• Authors: J Moyer.
• Comments: R-type calcium channel for nucleus accumbens neuron, uses ghk equation, written by j moyer 2004. Lists the following citations: churchill & macvicar (1998), foehring et al (2000), wang et al (1991), koch & segev (1998), hill (1992), and brevi et al (2001). This is the toxin-resistant current in fig 7 from churchill. No modeldb ancestors. Animal model is from experiments in paper. Channel data comes mostly from churchill & macvicar 1998, on adult rat accumbal cells.
• Runtime: 8.137
• Temperature: Model has temperature dependence. Experiments done at 33-35 deg C, simulations at 35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp