Channel 144523-CaHVA

General data

• ICG id: 1454
• ModelDB id: 144523
• Reference: Luthman J, Hoebeek FE, Maex R, Davey N, Adams R, De Zeeuw CI, Steuber V (2011): STD-dependent and independent encoding of input irregularity as spike rate in a computational model of a cerebellar nucleus neuron.

Metadata classes

• Animal Model: rat
• Brain Area: distal cerebellar nucleus (DCN)
• Neuron Region: soma, dendrites, distal dendrites, proximal dendrites
• Neuron Type: excitatory
• Runtime Q: Q1 (fast)
• Subtype: HVA

Metadata generic

• Age: P13-19
• Authors: J Luthman, V Steuber
• Comments: High-voltage activated calcium current of deep cerebellar nucleus (dcn) neuron, translation from genesis by j luthman and v steuber, uses ghk mechanism, calcium influx kept track by caconc.mod, affects the sk mod. Original model from steuber et al. (2011) in genesis. No modeldb ancestors. Modeling study, animal model is from experiments in ancestor model.
• Runtime: 7.168
• Temperature: Model has temperature dependence. Simulations were done at 37 deg C, and a temperature correction was performed on all channels using a Q10 of 3 for activation and 1.4 for inactivation.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp