Channel 140249-ical

General data

Metadata classes

  • Animal Model: mouse
  • Brain Area: lateral geniculate nucleus (LGN)
  • Neuron Region: soma, dendrites
  • Neuron Type: interneuron
  • Runtime Q: Q2
  • Subtype: high threshold

Metadata generic

  • Age: 29-33 days
  • Authors: A Destexhe, J Zhu, G Halnes.
  • Comments: High threshold calcium current, ca l-type channels, responsible for calcium spikes, from huguenard & mccormick 1992, data from kay and wong (1987), written by a destexhe sept 1992, modified by zhu et al. (1999), and g halnes jun 2011. Ancestor channel is from zhu et al. (1999), model no. 116862. Animal model reflects experimental procedures from this paper, which was used to constrain the model. Channel kinetics based originally on traub & miles (1991) model for hippocampal pyramidal neurons, later adapted by zhu et al. (1999) for thalamic interneurons, model no. 116862.
  • Runtime: 7.578
  • Temperature: Experiments and simulations done at 36 deg C, assumes q10=3, original activation kinetics at 21 deg C.

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp