Channel 139653-Ca_LVAst

General data

• ICG id: 1086
• ModelDB id: 139653
• Reference: Hay E, Hill S, Schurmann F, Markram H, Segev I (2011): Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: LVA

Metadata generic

• Age: P36
• Authors: E Hay
• Comments: Lva ca channel, from avery and johnston (1996), tau from randall (1997), shifted by -10mv to correct for junction potential, corrected rates, etc. No model db ancestors. Modeling study, that is constrained by experimental data (animal model here) (see le be et al. 2007). Channel kinetics come from various sources.
• Runtime: 7.343
• Temperature: Model has temperature dependence. Original temperature is 21 deg C. Here, qt is set to 2.3, to adjust kinetics for simulations at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp