Channel 135839-na

General data

• ICG id: 844
• ModelDB id: 135839
• Reference: Yu Y, Shu Y, McCormick DA (2008): Cortical action potential backpropagation explains spike threshold variability and rapid-onset kinetics.

Metadata classes

• Animal Model: ferret
• Brain Area: somatosensory cortex, layer 5, prefrontal cortex, cortex
• Neuron Region: soma, dendrites, axon, secondary dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: not specified

Metadata generic

• Age: 7-10 weeks old
• Authors: Z Mainen
• Comments: Sodium channel, hh style kinetics, fit to data from huguenard et al. (1988) and hamill et al. (1991), written by z mainen 1994. Taken from mainen & sejnowski (1996), model no. 2488, with no changes. The two papers contain electrophysiology results, reflected in the animal model info below, along with modeling study based on previous models.
• Runtime: 4.433
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C. SEE NOTE in mod file, should only be used at 37 deg C. Simulations done at 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp