Channel 128559-iNaP

General data

• ICG id: 801
• ModelDB id: 128559
• Reference: Aguiar P, Sousa M, Lima D (2010): NMDA channels together with L-type calcium currents and calcium-activated nonspecific cationic currents are sufficient to generate windup in WDR neurons.

Metadata classes

• Brain Area: dorsal horn of spinal cord
• Neuron Type: wide dynamic range (WDR) neuron
• Runtime Q: Q2
• Subtype: persistent

Metadata generic

• Authors: A Destexhe, A Houweling, S Prescott
• Comments: Persistent sodium, by a destexhe aug 1992 from traub & miles (1992), modified by a houweling, modified by s prescott also. Model appears to be from prescott & de koninck (2005), model no. 53569, with identical kinetics. Modeling study, with no mention of animal model. Channel kinetics come from previous study of hippocampal pyramidal neurons, adapted for spinal lamina i neurons (prescott & de koninck 2005).
• Runtime: 4.623
• Temperature: Model has temperature dependence, with q10 assumed to be 3. Original kinetics were formulated at 36 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp