Channel 123927-na3

General data

• ICG id: 552
• ModelDB id: 123927
• Reference: Wimmer VC, Reid CA, Mitchell S, Richards KL, Scaf BB, Leaw BT, Hill EL, Royeck M, Horstmann MT, Cromer BA, Davies PJ, Xu R, Lerche H, Berkovic SF, Beck H, Petrou S (2010): Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: not specified

Metadata generic

• Age: P14-P16
• Authors: unknown
• Comments: Na current modified from j magee, implemented by m migliore may 1997, added sh to account for higher threshold apr 2002. From royeck et al. (2008), no. 115356, with no modifications to kinetics. Experimental results and modeling, the animal model info here is from experiments, the model is the same as ancestor except for the na current.
• Runtime: 5.017
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp