Channel 206398-na16

General data

• ICG id: 4683
• ModelDB id: 206398
• Reference: Michalikova M, Remme MW, Kempter R (2017): Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma.

Metadata classes

• Animal Model: rat
• Brain Area: cortex
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Subtype: not specified

Metadata generic

• Age: P16–20 old
• Authors: Michalikova M, Remme MW, Kempter R
• Comments: COMMENT na16.mod Sodium channel, Hodgkin-Huxley style kinetics. Kinetics were fit to data from Huguenard et al. (1988) and Hamill et al. (1991) qi is not well constrained by the data, since there are no points between -80 and -55. So this was fixed at 5 while the thi1,thi2,Rg,Rd were optimized using a simplex least square proc voltage dependencies are shifted approximately from the best fit to give higher threshold Author: Zach Mainen, Salk Institute, 1994, zach@salk.edu ENDCOMMENT
• Temperature: temp = 23 (degC) : original temp, q10 = 2.3 : temperature sensitivity celsius (degC), tadj = q10^((celsius - temp)/10)

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp