Channel 117207-na

General data

• ICG id: 367
• ModelDB id: 117207
• Reference: Acker CD, Antic SD (2009): Quantitative assessment of the distributions of membrane conductances involved in action potential backpropagation along basal dendrites.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: layer 5, prefrontal cortex, cortex
• Neuron Region: soma, dendrites, axon
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: not specified

Metadata generic

• Age: P21-P33
• Authors: C Acker, Z Mainen
• Comments: Sodium channel, h-h style kinetics fit to data from huguenard et al. (1988) and hamill et al. (1991). By z mainen 1994, modified by c acker 2008 for temp adjustment factor. Inactivation kinetics modified to match kole et al. (2008). Taken from mainen & sejnowski (1996), model no. 2488, with several changes including modification to temperature adjustment. Experimental results mixed with modeling. The animal model info here is from the experiemntal results. Note that the ancestor channels are mostly from hippocampal pyramidal neurons.
• Runtime: 4.401
• Temperature: Model has temperature dependence, simulations done at 30 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp