Channel 155796-nav17

General data

• ICG id: 3362
• ModelDB id: 155796
• Reference: Chambers JD, Bornstein JC, Gwynne RM, Koussoulas K, Thomas EA (2014): A detailed, conductance-based computer model of intrinsic sensory neurons of the gastrointestinal tract.

Metadata classes

• Animal Model: guinea pig
• Brain Area: gastrointestinal tract
• Neuron Region: soma
• Neuron Type: intrinsic sensory neuron (ISN)
• Runtime Q: Q4 (slow)
• Subtype: 1.7

Metadata generic

• Age: not specified
• Authors: Unknown
• Comments: Nav1.7 current. Kinetic model based on the sheets nav1.7 model that also allows binding to inactivated states. From sheets et al. (2007). No apparent modeldb ancestors. Animal model is from experiments in paper. Channel kinetics were adapted from various sources. This channel was adapted from study of human nav1.7 channels (sheets et al 2007).
• Runtime: 8.662
• Temperature: No apparent temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp