Channel 149737-na

General data

• ICG id: 3198
• ModelDB id: 149737
• Reference: Wang K, Riera J, Enjieu-Kadji H, Kawashima R (2013): The role of extracellular conductivity profiles in compartmental models for neurons: particulars for layer 5 pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: layer 5, cortex
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: not specified

Metadata generic

• Age: juvenile (P14-16)
• Authors: A Korngreen
• Comments: Na channel, based on recordings from nucleated patches from l5 neocortical pyramidla neurons (a korngreen and sakmann, unpublished results), from keren et al. (2005). No apparent modeldb ancestors. Modeling study, with no experimental results. Authors mention that channel parameters were meant to match those of a juvenile rat (pg. 1818), so this is interpreted as the animal model. Otherwise, this can be considered generic.
• Runtime: 4.785
• Temperature: Model has temperature dependence. Original kinetics were at 21 deg C, and q10 is set to 2.3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp