1. Channels
  2. Na
  3. 144553-naz_nature

Channel 144553-naz_nature

General data

Metadata classes

  • Animal Model: monkey, rhesus monkey
  • Brain Area: visual cortex, prefrontal cortex, cortex, layer 3
  • Neuron Type: pyramidal cell
  • Runtime Q: Q2
  • Subtype: not specified

Metadata generic

  • Age: adult (5-11 years)
  • Authors: Z Mainen
  • Comments: Sodium channel, hh-style kinetics, fit to data from huguenard et al. (1988) and hamill et al. (1991), qi is not well constrained by the data, so no points between -80 and -55. V-dependencies are shifted approximately from the best fit to give higher threshold. By z mainen 1994. Paper cites mainen and sejnowski (1996) and vetter et al. (2001). Taken from mainen & sejnowski (1996), model no. 2488, with changes in implementation, but the same parameters. It is unclear if kinetics are modified. Animal model is from experiment in paper. Channel kinetics come from previous study using data from l5 pyramidal neurons (mainen & sejnowski 1996).
  • Runtime: 4.504
  • Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 23 deg C.

Current Response Traces

Activation
Inactivation
Deactivation
Action Potential
Ramp

ICGenealogy 0.3.5 © 2015-2016, CNCB, University of Oxford. All material on this page is in copyright. No reproduction of any part of it may take place without the written permission of the CNCB.