Channel 115356-na3

General data

• ICG id: 267
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, distal dendrites, apical dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: not specified

Metadata generic

• Age: 17-21 days
• Authors: M Migliore.
• Comments: Na current modified from jeff magee, implemented by m migliore may 1997, added sh to account for higher threshold. From migliore et al. (1999), model no. 2796, with no apparent changes. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics from migliore et al. (1999). The animal model info here is from the experiments in this paper.
• Runtime: 5.013
• Temperature: Model has temperature dependence, with default temperature of 24 deg C, and q10 from Migliore et al. (1999).

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp