Channel 8284-ichan

In other classes K

General data

• ICG id: 2404
• ModelDB id: 8284
• Reference: Chen K, Aradi I, Thon N, Eghbal-Ahmadi M, Baram TZ, Soltesz I (2001): Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Authors: I Aradi
• Comments: Sodium and potassium channel kinetics for control and ht cases. Model by i aradi. Model of ca1 pyramidal cells. Cites aradi & holmes (1999) (model no. 116740) for na / k dynamics, which were taken from yuen and durand (1991), but there are no mod files here for them. Animal model is from experiments in paper, used to fit ih currents. This channel's kinetics come originally from a previous study of hippocampal granule cells (aradi & holmes 1999).
• Runtime: 4.912
• Temperature: Model has temperature dependence, default at 6.3 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp