Channel 62673-mcna1e

General data

• ICG id: 2176
• ModelDB id: 62673
• Reference: Baranauskas G, Martina M (2006): Sodium currents activate without a Hodgkin-and-Huxley-type delay in central mammalian neurons.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1, prefrontal cortex, cortex, dentate gyrus (DG)
• Neuron Region: soma, dendrites, axon, proximal dendrites
• Neuron Type: pyramidal cell, granule cell
• Runtime Q: Q4 (slow)
• Subtype: not specified

Metadata generic

• Age: 4-7 weeks old for cortex, 16-18 day old for hippocampus
• Authors: G Baranauskas
• Comments: Two-closed one-open state sodium channel model, implemented by g baranauskas nov 2005, model fit to voltage clamp data in barnauskas and martina (2006). No model db ancestors. Experimental results and modeling. The animal model info here is from the experimental results, which came from cortex as well as hippocampus.
• Runtime: 5.48
• Temperature: Model has temperature dependence, with original kinetics at 13 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp