Channel 3342-na_v2

General data

• ICG id: 1788
• ModelDB id: 3342
• Reference: Shen GY, Chen WR, Midtgaard J, Shepherd GM, Hines ML (1999): Computational analysis of action potential initiation in mitral cell soma and dendrites based on dual patch recordings.

Metadata classes

• Animal Model: rat
• Brain Area: mitral cell layer, olfactory bulb (OB)
• Neuron Region: soma, dendrites, axon, axon hillock, axon initial segment (AIS), primary dendrites, dendritic tuft (apical tuft), axon nodes (nodes of ranvier), secondary dendrites
• Neuron Type: mitral cell
• Runtime Q: Q2
• Subtype: not specified

Metadata generic

• Age: 18-28 days
• Authors: US Bhalla, Z Mainen, M Hines
• Comments: Sodium channel, hh style kinetics, by bhalla 1993. Use with kd.mod. Note that the paper cites mainen and sejnowski 1995, but the mod file itself cites bhalla 1993. Taken from mainen & sejnowski (1995), model no. 8210, with various changes to parameters and procedure trates. This model is from the directory cell2, and shows a decrease in ap interval. It differs from the other na model in parameters and extra functions. Experimental results as well as modeling (expts described in chen et al. 1997). Morphology for model was created using known characteristics about mitral cells. The animal model info here is from the experimental methods.
• Runtime: 4.511
• Temperature: Model has temperature dependence, with original kinetics at 23 deg C, and q10 set to 2.3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp