Channel 20212-nap

General data

• ICG id: 1668
• ModelDB id: 20212
• Reference: Polsky A, Mel BW, Schiller J (2004): Computational subunits in thin dendrites of pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: dendrites, apical trunk
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: persistent

Metadata generic

• Authors: Y Poirazi
• Comments: Na persistent channel, used in oblique dendrites to assist ca spike initiation. A type in the exponential function was pointed out by m migliore and corrected by y poirazi 2003. There do not appear to be any model db ancestors. This is a modeling study, and the animal model is considered to be rat. The authors compare the model to experimental results mostly in rats (e.g. Magee 1998, spruston et al. 1995) and the morphology used is also from rat (2 months old, cannon et al. 1998, n123). Channel kinetics come from various sources.
• Runtime: 4.265
• Temperature: No apparent temperature dependence. Simulations were done at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp