Channel 144392-naxn

General data

• ICG id: 1332
• ModelDB id: 144392
• Reference: Shah MM, Migliore M, Brown DA (2011): Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: axon
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: not specified

Metadata generic

• Age: 5-6 weeks old
• Authors: M Migliore
• Comments: Na current for axon, no slow inactivation, implemented by m migliore jul 1997, added sh to account for higher threshold, 2002. From shah et al. (2008), with no modifications (identical mod file). Animal model info is from experiments here, which were coupled with modeling using the ancestor model, with morphology from migliore et al. (2005).
• Runtime: 4.785
• Temperature: Model has temperature dependence. Experiments done at 34-36 deg C, simulations at 35 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp