Channel 143671-na3rp

General data

• ICG id: 1246
• ModelDB id: 143671
• Reference: Powers RK, Elbasiouny SM, Rymer WZ, Heckman CJ (2012): Contribution of intrinsic properties and synaptic inputs to motoneuron discharge patterns: a simulation study.

Metadata classes

• Animal Model: mammal
• Brain Area: spinal cord
• Neuron Region: soma, dendrites, axon
• Neuron Type: motoneuron
• Runtime Q: Q4 (slow)
• Subtype: transient

Metadata generic

• Age: generic
• Authors: M Migliore, RK Powers
• Comments: Na current, modified from j magee by m migliore may 1997, added sh to account for higher threshold, m milgliore apr 2002, modified by rp to have slow inactivation from fleidervish et al. Taken from royeck et al. (2008), model no. 115356, with various changes. Modeling study. Not much information on how the model is constructed, but its performance is compared with some data from cat motoneurons. It is considered generic here because the paper does not mention any experiments that the model is based on.
• Runtime: 5.221
• Temperature: Model has temperature dependence, with original kinetics at 24 deg C. Simulations were run at 37 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp