Channel 123927-KM

General data

• ICG id: 544
• ModelDB id: 123927
• Reference: Wimmer VC, Reid CA, Mitchell S, Richards KL, Scaf BB, Leaw BT, Hill EL, Royeck M, Horstmann MT, Cromer BA, Davies PJ, Xu R, Lerche H, Berkovic SF, Beck H, Petrou S (2010): Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: m

Metadata generic

• Age: P14-P16
• Authors: unknown
• Comments: Originally based on warman 94, halliwell, adams 82. For details see previous model from royeck et al. (2008), no. 115356. Taken from royeck et al. (2008), no. 115356, with no modifications to kinetics. Experimental results and modeling, the animal model info here is from experiments, the model is the same as ancestor except for the na current.
• Runtime: 7.283
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp